AJSM Click here for details!
HOME HELP CONTACT US SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS
QUICK SEARCH:   [advanced]


     

Sign In to gain access to subscriptions and/or personal tools.
This Article
Right arrow Full Text
Right arrow Full Text (PDF)
Right arrow Alert me when this article is cited
Right arrow Alert me if a correction is posted
Right arrow Citation Map
Services
Right arrow Email this article to a friend
Right arrow Similar articles in this journal
Right arrow Similar articles in PubMed
Right arrow Alert me to new issues of the journal
Right arrow Download to citation manager
Right arrowRequest Permissions
Right arrow Request Reprints
Citing Articles
Right arrow Citing Articles via HighWire
Right arrow Citing Articles via Google Scholar
Google Scholar
Right arrow Articles by Johnson, D. L.
Right arrow Articles by Carlson, C. S.
Right arrow Search for Related Content
PubMed
Right arrow PubMed Citation
Right arrow Articles by Johnson, D. L.
Right arrow Articles by Carlson, C. S.
Related Collections
Right arrow Injury
Right arrow Chondral/cartilage
Right arrow Histology
The American Journal of Sports Medicine 26:409-414 (1998)
© 1998 American Orthopaedic Society for Sports Medicine

Articular Cartilage Changes Seen With Magnetic Resonance Imaging-Detected Bone Bruises Associated With Acute Anterior Cruciate Ligament Rupture

Darren L. Johnson, MD{dagger}, William P. Urban, Jr, MD, David N. M. Caborn, MD, William J. Vanarthos, MD and Cathy S. Carlson, DVM, PhD

Section of Sports Medicine, Division of Orthopaedic Surgery, University of Kentucky School of Medicine, Lexington, Kentucky

Presented at the interim meeting of the AOSSM, Atlanta, Georgia, February 1996.

{dagger} Address correspondence and reprint requests to Darren L. Johnson, MD, University of Kentucky, Section of Sports Medicine, 740 S. Limestone Street, K401, Lexington, KY 40536-0284

Occult osteochondral lesions (bone bruises) have been documented on magnetic resonance images in more than 80% of patients sustaining acute anterior cruciate ligament ruptures. Despite the high prevalence of these lesions, little is known about the histologic changes in the adjacent articular cartilage. Ten patients with acute anterior cruciate ligament ruptures who had a preoperatively documented (by magnetic resonance imaging) geographic bone bruise at the sulcus terminalis on the lateral femoral condyle underwent a 3-mm diameter trephine biopsy of the articular cartilage and subchondral bone overlying the bone bruise at the time of anterior cruciate ligament reconstruction. Biopsy samples of the articular cartilage and subchondral bone were stained with hematoxylin and eosin and toluidine blue. All patients had significant arthroscopic and histologic articular cartilage irregularity in the area overlying the bone bruise. Arthroscopic findings of the articular cartilage included softening (dimpling), fissuring, or overt chondral fracture. Histologic examination revealed degeneration of the chondrocytes and loss of toluidine blue staining in the articular cartilage (loss of proteoglycan). There was necrosis of osteocytes in the subchondral bone, and empty lacuna were visible. This study defines the exact histologic changes of the articular cartilage overlying a geographic bone bruise secondary to an acute anterior cruciate ligament tear. Our findings suggest that a geographic bone bruise found on magnetic resonance imaging indicates substantial damage to normal articular cartilage homeostasis.




This article has been cited by other articles:


Home page
 Am J Sports MedHome page
E. G. Meyer, T. G. Baumer, J. M. Slade, W. E. Smith, and R. C. Haut
Tibiofemoral Contact Pressures and Osteochondral Microtrauma During Anterior Cruciate Ligament Rupture Due to Excessive Compressive Loading and Internal Torque of the Human Knee
Am. J. Sports Med., October 1, 2008; 36(10): 1966 - 1977.
[Abstract] [Full Text] [PDF]

Home page
 Am J Sports MedHome page
S. Patil, W. Butcher, D. D. D'Lima, N. Steklov, W. D. Bugbee, and H. R. Hoenecke
Effect of Osteochondral Graft Insertion Forces on Chondrocyte Viability
Am. J. Sports Med., September 1, 2008; 36(9): 1726 - 1732.
[Abstract] [Full Text] [PDF]

Home page
 Am J Sports MedHome page
C. H. Yeow, C. H. Cheong, K. S. Ng, P. V. S. Lee, and J. C. H. Goh
Anterior Cruciate Ligament Failure and Cartilage Damage During Knee Joint Compression: A Preliminary Study Based on the Porcine Model
Am. J. Sports Med., May 1, 2008; 36(5): 934 - 942.
[Abstract] [Full Text] [PDF]

Home page
 Am J Sports MedHome page
D. G. Viskontas, B. M. Giuffre, N. Duggal, D. Graham, D. Parker, and M. Coolican
Bone Bruises Associated With ACL Rupture: Correlation With Injury Mechanism
Am. J. Sports Med., May 1, 2008; 36(5): 927 - 933.
[Abstract] [Full Text] [PDF]

Home page
 Am J Sports MedHome page
B. T. Hanypsiak, K. P. Spindler, C. R. Rothrock, G. J. Calabrese, B. Richmond, T. M. Herrenbruck, and R. D. Parker
Twelve-Year Follow-up on Anterior Cruciate Ligament Reconstruction: Long-term Outcomes of Prospectively Studied Osseous and Articular Injuries
Am. J. Sports Med., April 1, 2008; 36(4): 671 - 677.
[Abstract] [Full Text] [PDF]

Home page
 JBJSHome page
D.M. Green, P.C. Noble, J.R. Bocell Jr., J.S. Ahuero, B.A. Poteet, and H.H. Birdsall
Effect of Early Full Weight-Bearing After Joint Injury on Inflammation and Cartilage Degradation
J. Bone Joint Surg. Am., October 1, 2006; 88(10): 2201 - 2209.
[Abstract] [Full Text] [PDF]

Home page
 Am J Sports MedHome page
H. G. Potter and L. F. Foo
Magnetic Resonance Imaging of Articular Cartilage: Trauma, Degeneration, and Repair
Am. J. Sports Med., April 1, 2006; 34(4): 661 - 677.
[Abstract] [Full Text] [PDF]

Home page
 Am J Sports MedHome page
B. D. Beynnon, R. J. Johnson, J. A. Abate, B. C. Fleming, and C. E. Nichols
Treatment of Anterior Cruciate Ligament Injuries, Part I
Am. J. Sports Med., October 1, 2005; 33(10): 1579 - 1602.
[Abstract] [Full Text] [PDF]

Home page
 Am. J. Physiol. Regul. Integr. Comp. Physiol.Home page
R. M. Lovering and W. A. Romani
Effect of testosterone on the female anterior cruciate ligament
Am J Physiol Regulatory Integrative Comp Physiol, July 1, 2005; 289(1): R15 - R22.
[Abstract] [Full Text] [PDF]

Home page
 Am. J. Roentgenol.Home page
M. Bordalo-Rodrigues, M. Schweitzer, D. Bergin, R. Culp, and M. S. Barakat
Lunate Chondromalacia: Evaluation of Routine MRI Sequences
Am. J. Roentgenol., May 1, 2005; 184(5): 1464 - 1469.
[Abstract] [Full Text] [PDF]

Home page
 Am J Sports MedHome page
S. D. Mair, T. F. Schlegel, T. J. Gill, R. J. Hawkins, and J. R. Steadman
Incidence and Location of Bone Bruises After Acute Posterior Cruciate Ligament Injury
Am. J. Sports Med., October 1, 2004; 32(7): 1681 - 1687.
[Abstract] [Full Text] [PDF]

Home page
 Am J Sports MedHome page
D. L. Johnson, D. P. Bealle, J. C. Brand Jr, J. Nyland, and D. N.M. Caborn
The Effect of a Geographic Lateral Bone Bruise on Knee Inflammation After Acute Anterior Cruciate Ligament Rupture
Am. J. Sports Med., March 1, 2000; 28(2): 152 - 155.
[Abstract] [Full Text] [PDF]

Home page
 Am J Sports MedHome page
B. R. Mandelbaum, J. E. Browne, F. Fu, L. Micheli, J. B. Mosely Jr, C. Erggelet, T. Minas, and L. Peterson
Articular Cartilage Lesions of the Knee
Am. J. Sports Med., November 1, 1998; 26(6): 853 - 861.
[Full Text] [PDF]

Home page
 JBJSHome page
S. F. DYE, E. M. WOJTYS, F. H. FU, D. C. FITHIAN, and J. GILLQUIST
Instructional Course Lectures, The American Academy of Orthopaedic Surgeons - Factors Contributing to Function of the Knee Joint after Injury or Reconstruction of the Anterior Cruciate Ligament*{{dagger}}
J. Bone Joint Surg. Am., September 1, 1998; 80(9): 1380 - 1393.
[Full Text]


HOME HELP CONTACT US SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS
Copyright © 1998 by the American Orthopaedic Society for Sports Medicine.