HOME HELP CONTACT US SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS		QUICK SEARCH:   [advanced] Author: Keyword(s): Year:  Vol:  Page:
Sign In to gain access to subscriptions and/or personal tools.

This Article Full Text (PDF) Alert me when this article is cited Alert me if a correction is posted Citation Map Services Email this article to a friend Similar articles in this journal Alert me to new issues of the journal Download to citation manager Request Permissions Request Reprints Citing Articles Citing Articles via HighWire Citing Articles via Google Scholar Google Scholar Articles by Arnoczky, S. P. Articles by Minei, J. P. Search for Related Content PubMed Articles by Arnoczky, S. P. Articles by Minei, J. P.

Replacement of the anterior cruciate ligament using a synthetic prosthesis

An evaluation of graft biology in the dog

Laboratory of Comparative Orthopaedics and Sports Medicine Research, The Hospital for Special Surgery, affiliated with the New York Hospital, Cornell University Medical College, New York, New York

Russell F. Warren, MD, FACS

Laboratory of Comparative Orthopaedics and Sports Medicine Research, The Hospital for Special Surgery, affiliated with the New York Hospital, Cornell University Medical College, New York, New York

Joseph P. Minei, MD

Laboratory of Comparative Orthopaedics and Sports Medicine Research, The Hospital for Special Surgery, affiliated with the New York Hospital, Cornell University Medical College, New York, New York

The ACL of 21 adult mongrel dogs was replaced with a knitted dacron velour prosthesis. The biologic fate of these synthetic grafts was then evaluated at various intervals from 1 to 12 months postoperatively using routine histology and a vascular injection (Spalteholz) technique.

Following implantation the knitted dacron prosthesis was encapsulated with a vascular synovial tissue in a manner similar to that observed with autogenous pa tellar tendon grafts. This revascularization process was followed by a proliferation of fibroblasts throughout the extent of the prosthesis. While the grafts appeared to support a fibrous tissue proliferation in and around the design of the prosthesis, this tissue demonstrated only a random orientation of collagen fibers as late as 1 year postoperatively. It would appear, therefore, that al though the knitted dacron prosthesis is capable of inducing and supporting tissue encapsulation and in growth, it does not allow for the functional orientation of this tissue.

This article has been cited by other articles:

				W. A. Grana, D. M. Egle, R. Mahnken, and C. W. Goodhart An Analysis of Autograft Fixation After Anterior Cruciate Ligament Reconstruction in a Rabbit Model Am. J. Sports Med., June 1, 1994; 22(3): 344 - 351. [Abstract] [PDF]

				G. R. Barrett, L. L. Line JR, W. R. Shelton, J. O. Manning, and R. Phelps The Dacron ligament prosthesis in anterior cruciate ligament reconstruction: A four-year review Am. J. Sports Med., June 1, 1993; 21(3): 367 - 373. [Abstract] [PDF]

				H. N. Andersen, C. Bruun, and P. E. Sonergaro-Petersen Reconstruction of chronic insufficient anterior cruciate ligament in the knee using a synthetic Dacron prosthesis: A prospective study of 57 cases Am. J. Sports Med., January 1, 1992; 20(1): 20 - 23. [Abstract] [PDF]

				J. A. McCarthy, J. R. Steadman, J. Dunlap, R. Shively, and S. Stonebrook A nonparallel, nonisometric synthetic graft augmentation of a patellar tendon anterior cruciate ligament reconstruction: A model for assessment of stress shielding Am. J. Sports Med., January 1, 1990; 18(1): 43 - 49. [Abstract] [PDF]

				G. A. Brody, M. Eisinger, S. P. Arnoczky, and R. F. Warren In vitro fibroblast seeding of prosthetic anterior cruciate ligaments: A preliminary study Am. J. Sports Med., June 1, 1988; 16(3): 203 - 208. [Abstract] [PDF]